Ghostbusters as a whole is a great, funny movie that has great back and forth and, the thing I always loved, captures NYC in all of its 1980s glory but no one, NO ONE, can be Peter Venkman other than Bill Murray. The way he spins around outside Lincoln Center after he flirts with Dana. The way he says Walter Peck has no penis. The way he keeps shocking that dude in the beginning. The way he talks to the mayor to get him onboard with letting them save the day. "Lenny...."
The NYC thing I always loved: when Moranis starts talking to the horse, "wait for the sign, all prisoners will be released..." And the horse buggy guy is just like "he pulls the carriage, I make the deals" and then Moranis runs away all crazy and he tells YOU WILL PERISH IN FLAMES, and the driver isn't even freaked out he's just like "what an poopchute". freaking perfect.