Coronavirus SZN Forever

[Johnny English]

https://twitter.com/jackposobiec/status/1248300443442298882?s=21

I kept waiting for that car to say "Please put down your weapon. You have twenty seconds to comply."

[CatoTheElder]

https://twitter.com/jackposobiec/status/1248300443442298882?s=21

Didn’t look like they were breaking anything up at all. Also that comment section...holy excrement.

[SixFeetDeep]

Didn’t look like they were breaking anything up at all. Also that comment section...holy excrement.

Without looking, That guy I linked is Charlie Kirk tier

[CatoTheElder]

Without looking, That guy I linked is Charlie Kirk tier

Ughhhhhh.

[reuben]

Mask Game: 100

[SixFeetDeep]

I learned more about Tory Lanez this quarantine

[dcm1602]

Reading about the protocols in place in China are insane.

They need to have a smart phone app proving they tested negative to leave their houses in Wuhan

If there's a resurgence in China this excrement isn't leaving the USA until there's a cure vaccine or heard immunity from most people getting it. Panic levels would instantly blow away anything we've seen

There's just so much fucked up stuff with China atm. Their restrictions are insane and this corruption with them and the WHO is quite scary

[bojanglesman]

The wall will block it.  Yuge.

[Pope]

Reading about the protocols in place in China are insane.

They need to have a smart phone app proving they tested negative to leave their houses in Wuhan

If there's a resurgence in China this excrement isn't leaving the USA until there's a cure vaccine or heard immunity from most people getting it. Panic levels would instantly blow away anything we've seen

There's just so much fucked up stuff with China atm. Their restrictions are insane and this corruption with them and the WHO is quite scary

What difference does it make, it’s already here

[dcm1602]

What difference does it make, it’s already here

Because it seems that as of this week everything is turning the corner. Numbers are improving in almost every metric, models are being revised much lower. People actually seem somewhat hopeful

If suddenly people realize that this shits going to be here to stay for the next year, that's a big change. I mean this shits been legit for what 6 weeks? What happens when people realize there's another 60 to go

[Miamipuck]

Because it seems that as of this week everything is turning the corner. Numbers are improving in almost every metric, models are being revised much lower. People actually seem somewhat hopeful

If suddenly people realize that this shits going to be here to stay for the next year, that's a big change. I mean this shits been legit for what 6 weeks? What happens when people realize there's another 60 to go

There is another 60 to go at the very least.

[SixFeetDeep]

https://www.cnn.com/2020/04/10/asia/china-wildlife-law-coronavirus-intl-hnk/index.html

"With the progress of human civilization and the public's concern and preference for animal protection, dogs have evolved from traditional livestock to companion animals," said an accompanying explanation of the draft. "They are generally no longer regarded as livestock in the rest of the world. It is not advisable to list them under livestock or poultry in China."

[Derek Smalls]

Because it seems that as of this week everything is turning the corner. Numbers are improving in almost every metric, models are being revised much lower. People actually seem somewhat hopeful

If suddenly people realize that this shits going to be here to stay for the next year, that's a big change. I mean this shits been legit for what 6 weeks? What happens when people realize there's another 60 to go

The problem is there are a lot of stupid people in the world. Most intelligent people say, "People social distanced and the numbers have started to go down. Great!" But there are a lot of people who say, "See? I told you they were lying about this coronavirus nonsense, it's not that big of a deal - let's have an orgy."

[dcm1602]

The problem is there are a lot of stupid people in the world. Most intelligent people say, "People social distanced and the numbers have started to go down. Great!" But there are a lot of people who say, "See? I told you they were lying about this coronavirus nonsense, it's not that big of a deal - let's have an orgy."

Well if you use a condom you won't get Corona so it's okay

[Miamipuck]

https://www.bloomberg.com/news/articles/2020-04-10/two-thirds-of-severe-covid-19-improved-on-gilead-s-remdesivir?srnd=premium&sref=yP39NlD2

Two-Thirds of Severe Covid-19 Cases Improved on Gilead Drug
By Michelle Fay Cortez, Robert Langreth, and Jason Gale
April 10, 2020, 5:22 PM EDT Updated on April 10, 2020, 9:44 PM EDT
 Patients got experimental drug on a compassionate use basis
 




Gilead Sciences Inc.’s experimental drug for patients with severe Covid-19 infections showed promise in an early analysis, raising tentative hope that the first treatment for the novel virus may be on the horizon.

The report published in the New England Journal of Medicine tracked 53 people in the U.S., Europe and Canada who needed respiratory support, with about half receiving mechanical ventilation and four on a heart-lung by-pass machine. Eight additional patients were left out of the analysis: one due to a dosing error and seven because no information was available on how they fared.

All received remdesivir for up to 10 days on a compassionate use basis, a program that allows people to use unapproved medicines when no other treatment options are available. Over 18 days, 68% of the patients improved, with 17 of the 30 patients on mechanical ventilation being able to get off the breathing device. Almost half of the patients studied were ultimately discharged, while 13% died. Mortality was highest among those who were on a ventilator, with 18% of them dying.


“We cannot draw definitive conclusions from these data, but the observations from this group of hospitalized patients who received remdesivir are hopeful,” said lead author Jonathan Grein, director of hospital epidemiology at Cedars-Sinai Medical Center in Los Angeles, in a statement from Gilead. The Foster City, California-based company provided the medication and also helped analyze the results.

Several large scale clinical trials are underway to evaluate the benefit of remdesivir for Covid-19, the disease caused by the novel coronavirus that has infected more than 1.65 million people worldwide and killed 100,000. One that was conducted in China could report results this month. Another, sponsored by the U.S. National Institutes of Health, has enrolled patients rapidly as the virus spread throughout the U.S. It could also report results in the coming weeks. Gilead itself is sponsoring an additional two trials.

‘Answers Are Needed’
“In studying remdesivir, the question is not just whether it is safe and effective against Covid-19, but in which patients it shows activity, how long should they receive treatment and at what stage of their disease would treatment be most beneficial,” said Daniel O’Day, Gilead’s chairman and chief executive officer. “Many answers are needed, which is why we need multiple types of studies involving many types of patients.”

Some of these answers will emerge in the coming weeks with the release of initial data from the various clinical trials, O’Day said Friday in an open letter sent via email.

There are currently no treatments proven to work specifically against the coronavirus infection. Gilead has provided the medicine to more than 1,800 patients on a compassionate use basis.

Cheap to Make
If it’s shown to be safe and effective for treating Covid-19, the medication is estimated to cost about $9 a treatment to make, said Andrew Hill, a senior visiting research fellow in the pharmacology department at Liverpool University, and colleagues in a study Friday.

As an intravenous infusion, there would be additional costs to administer remdesivir, which are likely to exceed the estimated manufacturing, the authors said.

Potential Coronavirus Drugs May Cost as Little as $1, Study Says

Results of controlled studies of remdesivir are highly anticipated because they will be some of the first rigorous large scale studies completed on potential anti-coronavirus drugs.

President Donald Trump and others have touted the potential of hydroxychloroquine, an old malaria and lupus drug, for treating Covid-19. But that drug hasn’t yet been carefully studied in a large trial to see if it prevents severe complications. Most of the excitement stems from relentless social media promotion of a tiny French study whose methodology has been heavily criticized by many U.S. medical experts.


Remdesivir, a broad-spectrum antiviral, is viewed by researchers and doctors as one of the most promising agents against Covid-19 to enter human trials to date. In lab studies conducted prior to the Covid-19 outbreak on numerous compounds, researchers at the University of North Carolina and Vanderbilt University found the drug had potent activity against against a wide variety of coronaviruses similar to the new coronavirus.

Tested for Ebola
Because it had already been tested in patients with Ebola, where it was shown to be safe but ineffective, researchers were able to quickly begin studying it human trials when the Covid-19 pandemic hit.

About one in four patients on the medicine experienced severe side effects, including multiple-organ dysfunction syndrome, septic shock, acute kidney injury and low blood pressure. Another 23% showed signs of liver damage on laboratory tests. Four patients had to stop receiving infusions of the drug entirely.

Remdesivir was considered to be the most promising therapeutic candidate based on its broad antiviral spectrum, and existing data based on human and animal studies, a World Health Organization panel said in January. The medication was developed initially for Ebola and studied in patients in Eastern Congo.

If it works well, one issue will be whether there is enough of a supply of the drug, especially if the epidemic is still raging. Gilead has been working all-out to bolster supply of the hard-to-make medicine. It said earlier this month that it hopes to to have 500,000 treatment courses by October, and more than 1 million by year-end. Production time has also been accelerated to six months from one year.

(Adds Gilead executive’s comments in sixth paragraph; estimated manufacturing cost in ninth.)